Biguanide-atovaquone synergy against Plasmodium falciparum in vitro.
نویسندگان
چکیده
The synergistic potential of a range of biguanides, their triazine metabolites, tetracyclines, and pyrimethamine in combination with atovaquone has been assessed. All five biguanides tested interacted synergistically with atovaquone against Plasmodium falciparum in vitro. All of the other compounds tested were either additive or antagonistic.
منابع مشابه
Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum.
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 46 8 شماره
صفحات -
تاریخ انتشار 2002